Quinoline derivatives, their preparation and therapeutic compositions containing the same
CA 1291136 C · Owner: Esanu, Andre · Inventors: Esanu, Andre
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to new quinoline derivatives of the formula :, wherein R stands for C2H5 C2H4F, CH2-O-CH2-CH2OH, CH2 , , or , to a process for their preparation comprising reacting for, 12-24 hours, at 70 - 95°C, in dimethylformamide the, 1,4-dihydro- 3-ethoxycarbonyl- 6,8- difluoro-4-oxo-quinoline with an excess of RX (2-5 mol of RX for one mol of quinoline) in the presence of K2CO3 and subsequently hydrolysing the obtained 3-ester by HCl under reflux conditions and to pharmaceutical compositions comprising at least one 1,4-dihydro- 3-carboxy- 6,8-difluoro- 1-R-4-oxo-quinoline derivative in admixture with a pharmaceutically acceptable diluent or carrier.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted October 22, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended October 22, 2008.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.