Optically active 2-chloro-12-(3-dimethylamino-2- methylpropyl)-12h-dibenzo ¬d,g ¬1,3,6 dioxazocines and a process for the preparation thereof
CA 1291133 C · Owner: Gigler, Gabor · Inventors: Gigler, Gabor; Rozsa, Laszlo; Petocz, Lujza
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OPTICALLY ACTIVE 2-CHLORO-12-(3-DIMETHYLAMIMO-2-METHYL- PROPYL)-12H-DIBENZOd,g1,3,6DIOXAZOCINES AND A PROCESS FOR THE PREPARATION THEREOF, A b s t r a c t The invention relates to optically active 2- -chloro-12-(3-dimethylamino-2-methylprcpyl)-12H-dibenzo- d,g 1,3 9 6dioxazocines of the formula (I), and pharmaceutically acceptable acid addition salts thereof. The enantiomers are especialiy active against Parkinson's disease. The optically active enantlomers are prepared by a) resolving the racemic 2-chloro-12-(3-dimethylamino-2-methylprcpyl)-12H-dibenzod,g1,3,6 dioxazocine with an optically active organic acid and separating the enantiomers; or b) dissolving the racemic …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
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- Granted October 22, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended October 22, 2008.
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