Chemical complex of potassium acetylsalicylate and preparation thereof

Abstract From the Canadian patent

A substantially stable and relatively nonhygroscopic complex corresponding to substantially equimolar quantities of acetylsalicylic acid, potassium acetylsalicylate and potassium bicarbonate, which exhibits properties as a nonphysical mixture, and process for preparing it are, provided. The process comprises reacting about 1 mole of acetylsalicylic acid with about one-half mole of potassium carbonate in a major amount of organic solvent and a minor amount of water to form the aforementioned complex. The complex readily dissolves in water with formation of a neutral solution of an aspirin salt, i.e. potassium acetylsalicylate. It offers potassium acetylsalicylate in a substantially stable …