Quinazolinone compounds and processes for the preparation thereof

Abstract From the Canadian patent

The present invention is directed to quinazolinone compounds of the formula:, (I), wherein R is a hydrogen atom or a lower alkyl R1 is a, lower alkyl, a phenyl, a phenyl substituted by a member selected from the group consisting of a lower alkyl and a halogen atom or phenyl-C1-3 alkyl and R2 R3, R4, and R5 are the same or different and each represent a hydrogen atom, a halogen atom, a lower alkyl a lower, alkoxy, a lower alkoxycarbonyl or a lower alkoxycarbonyllower alkenyl, or two adjacent groups of R2 R3, R4, and R5 when taken together form methylenedioxy and the other two are hydrogen atoms, or a salt thereof. These compounds are useful for the prophylaxis and treatment of various …