Anti-human ovarian cancer immunotoxins and methods of use thereof
CA 1287578 C · Owner: Cetus Corporation · Inventors: Frankel, Arthur E.; Laird, Walter J.; Bjorn, Michael J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Immunotoxins comprising a cytotoxic moiety and an antigen binding portion selected from the group consisting of Fab Fab' and, F(ab')2 fragments of a monoclonal antibody which binds to human, ovarian cancer tissue having one of the following capabilities are claimed: cytotoxic ID50 of about 10 nM or less against human ovarian cancer cells, retardation of human ovarian cancer tumor growth in mammals, or extension of survival of a mammal carrying a human ovarian cancer tumor. Antigens or epitopes to which the monoclonal antibodies bind are identified and characterize the immunotoxins. In a preferred embodiment an immunotoxin comprising at least an antigen binding portion of a monoclonal …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted August 13, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended August 13, 2008.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.