1-phenoxy-propyl-4-¬n(phenyl)-thiocarbamoyl or carbamoyl - trans-decahydroquinoline compounds

Abstract From the Canadian patent

The invention relates to novel decahydroquinolinol derivatives represented by the general formula: and pharmaceutically acceptable acid addition salts thereof in which X represents oxygen or sulphur R represents an, alkyl radical having from 1 to 3 carbon atoms R1 represents, fluorine, chlorine, bromine or methoxy R2 represents, hydrogen or methoxy or R1 and R2 when they are taken, together, represent a 2,3-methylenedioxy or 3,4-methylenedioxy radical. These derivatives are inhibitors of calcium translocation at the level of the cell membrane and are useful more particularly in the treatment of pathological syndromes of the cardiovascular system such as for, instance, angina pectoris.