Cycloalkyl-substituted-4-aminophenyl derivatives and process for their preparation
CA 1285287 C · Owner: Farmitalia Carlo Erba S.P.A. · Inventors: Di Salle, Enrico; Lombardi, Paolo; Crugnola, Angelo
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to cycloalkyl substituted 4-aminophenyl derivatives of formula (I), (I), wherein R is C1-C4 alkyl:, n is an integer of 1 to 5; and either (a) A is ?C=O and B is -O-, -NH- or -CH2-; or (b) A is -CH2- and B is -O-, -NH-, -CH2- or ? C=O; or (c) A is -O- and B is ?C=O or -CH2-; or (d) A is -NH- and B is ?C=O or -CH2- , and their pharmaceutically acceptable salts. The scope of the invention includes also a process for preparing the said compounds of formula (I) and pharmaceutical compositions containing same. The compounds of the invention show aromatase inhibiting activity and can be useful, e.g. in treating hormone-dependent tumors and prostatic hypertrophy or hyporplasia.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted June 25, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended June 25, 2008.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.