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Expired Canadian patentCanada

Methods and compositions for the detection of familial hypercholesterolemia

CA 1280378 C · Owner: Goldstein, Joseph L. · Inventors: Brown, Michael S.; Goldstein, Joseph L.; Russell, David W.

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Abstract From the Canadian patent

Recombinant DNA transfer vectors containing DNA inserts which are complementary to either the human LDL receptor gene, or its mRNA transcript, are disclosed. Also disclosed are methods which utilize these genetic probes for diagnosing Familial Hypercholesterolemia (FH) in a suspected individual. A case study of one such individual, FH 274, is disclosed wherein the genetic deletion mutation is detailed with great precision through the practice of this invention.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Granted February 19, 1991. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended February 19, 2008.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledDecember 30, 1985
GrantedFebruary 19, 1991
Term endedFebruary 19, 2008
Patent numberCA 1280378 C
Classification (IPC)C12N13/00 +1 more

Timeline

Timeline From CIPO dates

19861989199219951998200120042007Application filedDec 30, 1985Patent grantedFeb 19, 1991Term endedFeb 19, 2008

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.