5-arylalkyl-4-alkoxy-2(5h)-furanones, intermediates and processes for the preparation thereof and medicaments containing them

Abstract From the Canadian patent

5-Arylalkyl-4-alkoxy-2(5H)-furanones intermediates, and processes for the preparation thereof and medicaments containing them, The present invention provides 5-arylalkyl-4alkoxy-2(5H)-furanones of the general formula:- (I), wherein the oxygen atoms on C-5 and C-.alpha. relative to one another, are in the threo-position with the exclusion, of those compounds of general formula (I) wherein R2 is H or CH3 when n = 0 or 2, Ro = H, R1 = CH3 R3 = H and, R4 = H. The present invention also provides processes for their preparation, as well as new 3-alkoxy-5-(subst.)phenyl-2(E),4(E)-pentadienoates as reactive intermediates for the preparation of the new furanone derivatives. The new furanone …