Oxygenated-alkyl derivatives of glutamic and aspartic acids with antagonistic activity to bio-active polypeptides and a method for their preparation
CA 1269110 C · Owner: Rotta Research Laboratorium S.P.A. · Inventors: Chiste', Rolando; Rovati, Luigi; Rovati, Lucio
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New original derivates of D,L-glutamic acid and D,L-aspartic acid are described having the formula: (I), where n is 1 or 2, R1 is a mono- or di-substituted phenyl group substituted with halogens such as chlorine and fluorine or with a methyl group in the 3 and 4 positions and in which R2 consists of a linear or branched alkyl group with 4 to 7 carbon atoms (preferably a pentyl group) and R3 is an alkyl group having 3 to 6 carbon atoms overall and containing an oxygen atom in the form of an ether linkage such as for, example the groups 2-ethoxyethyl 3-methoxypropyl, 3-ethoxypropyl etc. or in the form of a hydroxyl group such as for example 3-hydroxypropyl etc. The compounds have antagonistic …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted May 15, 1990. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended May 15, 2007.
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