Quinoline derivatives, pharmaceutical compositions containing them and process for the preparation thereof

Abstract From the Canadian patent

A b s t r a c t The invention relates to new quinoline derivatives of the general Formula I, (I), (wherein X stands for hydrogen, halogen or lower alkoxy; n is an integer of 1, 2 or 3;, R1 represents hydrogen and R2 represents hydroxy-lower alkyl or lower alkoxy-lower alkyl or a group of the general Formula IV (IV), wherein, Z stands for -O-, -S-, -NH- or -N(lower alkyl)-; the dotted lines represent optional bonds; and m is 0 or 1; or, R1 and R2 together with the adjacent nitrogen atom they, are attached to, form a 5- or 6-membered heterocyclic group which may optionally contain a further oxygen, nitrogen or sulfur heteroatom and may be optionally substituted), and pharmaceutically …