Monoclonal antibody to candida albicans cytoplasmic antigens and methods of preparing same
CA 1266233 C · Owner: Strockbine, Nancy A. · Inventors: Largen, Michael T.; Strockbine, Nancy A.; Buckley, Helen R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Abstract Two novel hybridoma cell lines, ATCC #HB-8397 and ATCC #HB-8398 produce monoclonal antibody monospecific to a single determinant shared by a set of three closely related cytoplasmic antigens of Candida albicans. The antigens have molecular weights of 120-135 Kd, 48-52 Kd and 35-38, Kd. The hybridomas are formed by fusing splenocytes from immunized BALB/c mice with SP2/O-Ag 14 myeloma cells. Monoclonal and monospecific polyclonal antibodies to these, cytoplasmic antigens find application in the immunodiagnosis of Candida infections. A procedure is provided for preparing partially purified cytoplasmic antigen of pathoganic Candida species for administration to splenocyte-donating …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted February 27, 1990. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended February 27, 2007.
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