SUBSTITUTED .beta.-CARBOLINES, PROCESS FOR THE PREPARATION THEREOF, AND USE THEREOF AS MEDICINAL AGENTS

Abstract From the Canadian patent

Novel substituted .beta.-carboline derivatives of Formula I wherein , R3 is an oxadiazolyl residue of the formula wherein R5 stands for lower alkyl of up to 3 carbon atoms or an ester ?-OR6 with R6 being hydrogen or lower alkyl of up to 3 carbon atoms, R4 is hydrogen lower alkyl of up to 3 carbon atoms, or CH2OR9 wherein R9 is lower alkyl of up to 3 carbon atoms, RA is phenyl or a hydrocarbon residue containing 2-10 carbon atoms which can be cyclic or acyclic satur-, ated or unsaturated, branched or unbranched and, which can optionally be substituted by oxo formyl, OH, O-alkyl of up to 3 carbon atoms or phenyl and, wherein, in a cyclic hydrocarbon residue a CH2-, group can be replaced by …