Thromboxane a.sub.2 synthetase inhibitory 1-(3-pyridyl)-1-alkene derivatives and their production and use

Abstract From the Canadian patent

Novel compounds of the formula: wherein R2 is an aromatic or heterocyclic group which may op-, tionally be substituted R2 is a methyl group, a hydroxymethyl, group a nitroxymethyl group, a formyl group, a nitrogen-containing five-membered ring-methyl group an acetal-methyl group, a trialkylsilyloxymethyl group an alkyl- or aryl-sulfonyloxy-, methyl group an alkyl- or aryl-sulfonylaminocarbonyloxymethyl group, an acyloxymethyl group, an alkoxycarbonyloxymethyl group a halogenomethyl group, an alkoxymethyl group an aryloxymethyl, group, a cyano group a carbamoyl group which may optionally be substituted, a carbamoyloxymethyl group which may optionally be substituted, a thiocarbamoyloxymethyl …