10,11-dihydro-5h-dibenzo a,d cycloheptadiene derivatives, their preparation and their use

Abstract From the Canadian patent

By reacting a suitable oxirane with a suitable amine, 10,11-dihydro-5H-dibenzoa,dcycloheptadiene derivatives of general formula (I):, (I), where R1 is hydrogen C1-C6-alkyl, C2-C6-alkenyl, C2-C6-, alkynyl C1-C6-hydroxyalkyl or C1-C4-alkoxy-C1-C4-alkyl and R2 is hydrogen, or R1 and R2, together with the nitrogen atom which connects them to one another form a morpholine, ring or a piperidine ring which may be substituted in the 4position by hydroxyl and/or by unsubstituted or halogensubstituted phenyl, are produced. These substances and, their salts with physiologically tolerated acids are useful, for the treatment of disorders such as in arrhythmias therapy.