Diffusion coated multiple-units dosage form

Abstract From the Canadian patent

Diffusion Coated Multiple-Units Dosage Form ABSTRACT, In an oral pharmaceutical controlled release multiple-units formulation individual units containing an active substance are coated with a substantially water-insoluble, but water-diffusible controlled release coating which includes, 1) an inner film layer comprising a homogeneous combination of a water-dispersible film-forming agent and a polymeric substance which imparts compressibility to the coating and, 2) optionally an outer film layer comprising a film-forming agent which prevents adhesion between the units at elevated temperatures and imparts flowability to the units. The coating possesses a sufficient plastic deformability to …