Intermediates for preparing substituted 1-piperazine- carboxamides and use thereof

Abstract From the Canadian patent

Intermediates which are 1-piperazinecarboxylates or the general formula I, (I), wherein R2, R3 R4, R5 are groups independently selected from hydrogen, lower alkyl having from 1 to 3 carbon atoms and phenyl, R6 is a group selected from hydrogen F, C1, Br, lower alkoxy having from 1 to 3 carbon atoms and -CF3- -groups, R1 represents either an unsubstituted or substituted aryl group with good leaving group properties suitably, a phenyl or a para-nitro-phenyl groupfor producing, 1-piperazinecarboxamides of the general formula II (II), wherein R7 and R8 are groups independently selected from the group of hydrogen, alkyl straight or branched chains having from 1 to 10 carbon atoms, cycloalkyl …