Process for the preparation of 3,4-di-isobutyryloxy-n- methyl-phenethylamine
CA 1236848 A · Owner: Farmos - Yhtyma Oy · Inventors: Eloranta, Marie M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process is provided herein for the preparation of Nbenzyl-N-methyl-3,4-di-isobutyryloxyphenethylamine of the Formula (IV), (IV), or its acid addition salt. The process involves esterifying Nbenzyl-N-methyl-3,4-di-hydroxy-phenethylamine with isobutyryl chloride and an organic base in an organic solvent. This compound (IV) is an intermediate for the preparation of the therapeutically active compound, 3,4-di-isobutyryloxy-N-methylphenethyl-amine (I), (I), or its acid-addition salts. Compound (I) also known as, ibopamine, is a well-known cardiac medicine which is used, especially in heart and kidney insufficiency.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted May 17, 1988. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended May 17, 2005.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.