Method of biosynthesis and cells therefore

Abstract From the Canadian patent

There is provided an expression vector having two structural genes that form a synthetic operon expressed under the control of a single regulatory sequence. The operon genes correspond to the structural component of naturally occurring genes whose expression is controlled by distinct separate regulatory sequences. The operon genes code for enzymes in a biosynthetic pathway for producing a desired compound and at least one, of those operon genes is feedback derepressed. The vector is used to transform host cells that are cultured to produce the desired product.