3-(ureidocyclohexylamino)-propane-1,2-diol- derivatives

Abstract From the Canadian patent

3-(Ureidocyclohexylamino)-propane-1,2-diol-derivatives Abstract of the disclosure, The invention concerns antihypertensive and cardiocative compounds of the formula I, (I), wherein Ar represents a (monocyclic or optionally partially hydrogenated bicyclic) carbocyclic or heterocyclic optionally substituted aromatic radical; R represents hydrogen alkanoyl or aroyl; R1 and, R2 represent independently hydrogen or lower alkyl; or R1 and R2 combined represent alkylene of 2 to 7 carbon atoms separating the two nitrogen atoms thereto attached by 2 to 4 carbon atoms; R3 and R4 independently are hydrogen or lower alkyl; and X represents oxo (O) or thio (S); and salts thereof. They are prepared for …