Process for the preparation of 5,6,7,7a, tetrahydro- 4h-thieno 3,2-c pyridin-2-ones

Abstract From the Canadian patent

The present invention provides a process for the preparation of 5,6,7,7a-tetrahydro-4H-thieno3,2-cpyridin-2-ones of the general formula:in which R is a hydrogen atom or a phenyl radical optionally substituted by at least one halogen atom lower alkyl radical, lowar alkoxy radical nitro group, carboxyl group or alkoxycarbonyl radical R' is a, hydrogen atom or lower alkyl radical and n is 0 or a number of from 1 to 4, wherein a compound of the general formula:-, in which R, R' and n have the same meaning as above is reacted with formaldehyde to give a compound of the general formula:-, in which R, R' and n have the same meanings as above whereafter this compound is treated with dry hydrogen …