2-imidazoline derivatives, process for the preparation thereof and the pharmaceutical composition of the same

Abstract From the Canadian patent

New 2-imidazoline derivatives are provided of the formula:, (1), wherein R1 is aryl which may have 1 to 5 substituents(s) selected from the groups, consisting of halogen lower alkyl, lower alkoxy, lower alkanesulfonamido, mono(alkyl), carbomoyl, hydroxy nitro, amino, cyano, sulfamoyl, N,N-di(lower)alkylsulfamoyl and, di(lower)alkylamino which may form a 3 to 7-membered ring with or with-, out an oxygen or nitrogen atom; R2 and R3 are each hydrogen, halogen, lower alkyl lower alkoxy, lower, alkanesulfonamido mono(or di or, tri)?halo(lower)alkyl, carbamoyl hydroxy, nitro, amino, cyano, sulfamoyl N,N-di(lower)alkyl-, sulfamoyl, or di(lower)alkylamino which may form a 3 to 7-membered, ring with …