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Expired Canadian patentCanada

Immunochemical conjugates: method and composition

CA 1138438 A · Owner: Scripps Clinic And Research Foundation · Inventors: Katz, David H.

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Abstract From the Canadian patent

Techniques for preparing stable conjugates of protein-?-GL which can then be isolated in pure form are disclosed, using hen egg ovalbumin (OVA) as a prototype protein, and conjugation and purification methods are described which involve 1) application of a coupling method employing m-maleimidobenzoyl-Nhydroxysuccinimide ester (MBS) as the coupling reagent, and 2) introduction of biotin moieties into ?-GL molecules to allow application of avidinbiotin system for affinity chromatographic purification of conjugates. These methods are applicable to the preparation of ?-GL conjugates of insulin and Ragweed Antigen E and are of general applicability.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Granted December 28, 1982. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended December 28, 1999.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledJanuary 17, 1980
GrantedDecember 28, 1982
Term endedDecember 28, 1999
Patent numberCA 1138438 A
Classification (IPC)A61K39/00 +2 more

Timeline

Timeline From CIPO dates

1981198319851987198919911993199519971999Application filedJan 17, 1980Patent grantedDec 28, 1982Term endedDec 28, 1999

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.