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Expired Canadian patentCanada

Hepatitis a virus cell culture in vitro

CA 1135621 A · Owner: Merck & Co. Inc. · Inventors: Hilleman, Maurice R.; Provost, Philip J.

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Abstract From the Canadian patent

Hepatitis A virus is passaged at least once in a susceptible sub-human primate; the infected liver from such passage is used to inoculate an in vitro cell culture, the inoculated cell culture is incubated until hepatitis A antigen is detected in the cell sheet or culture fluid, and at least two serial in vitro passages in cell culture are carried out. The hepatitis A virus so modified can be used to prepare live, attenuated hepatitis A vaccine or an inactivated hepatitis A vaccine.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Granted November 16, 1982. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended November 16, 1999.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledAugust 7, 1979
GrantedNovember 16, 1982
Term endedNovember 16, 1999
Patent numberCA 1135621 A
Classification (IPC)A61K39/29

Timeline

Timeline From CIPO dates

1980198219841986198819901992199419961998Application filedAug 7, 1979Patent grantedNov 16, 1982Term endedNov 16, 1999

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.