Imidazo 1,2-a imidazoles, their acid addition salts, pharmaceuticals comprising same and processes for their production thereof

Abstract From the Canadian patent

Imidazo1,2-aimidazoles of general formula I, (wherein R1, R2 and R3 independently represent hydrogen fluorine, chlorine, bromine, methyl, methoxy or trifluoromethyl but at least one of R1, R2 and, R3 is other than hydrogen; R4 and R5 independently represent hydrogen or methyl) and pharmaceutically acceptable acid addition salts thereof. The compounds have been found to decrease heart beat frequency and may therefore be useful in the treatment of coronary diseases. Processes for the preparation of the compounds, and pharmaceutical compositions containing them are, described and exemplified.