Process for the rearrangement of 10,11-epoxy-10,11- dihydro-5h-dibenz¬b,f azepine-5-carboxamide to 10- oxo-10,11-dihydro-5h-dibenz¬b,f azepine-5- carboxamide
CA 1112241 A · Owner: Novartis Ag · Inventors: Zergenyi, Janos; Heckendorn, Roland; Menard, Enrico
Overview
Its claims, description and drawings are in the Canadian Patents Database.
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Process for the rearrangement of 10,11-epoxy-10,11-dihydro- 5H-dibenzb,fazepine-5-carboxamide to 10-oxo-10,11dihydro-5H-dibenzb,fazepine-5-carboxamide Abstract, The invention relates to a process for the rearrangement of 10,11-epoxy-10,11-dihydro-5H-dibenzb,fazepine 5-carboxamide of the formula, to 10-oxo-10,11-dihydro-5H-dibenzb,fazepine-5carboxamide of the formula, which process comprises performing the rearrangement by means of a bromide or iodide of lithium magnesium or, calcium in the dry form, or in the form of their known compounds with water (hydrates) or with organic substances in a suitable solvent within a temperature range of 20 - 120°C, preferably of 40 - 80°C.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted November 10, 1981. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended November 10, 1998.
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