Synthesis of 2-amino-2-deoxyglycoses and 2-amino-2- deoxyglycosides from glycals
CA 1111417 A · Owner: Ratcliffe, Robert M. · Inventors: Lemieux, Raymond U.; Ratcliffe, Robert M.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
SYNTHESIS OF 2-AMINO-2-DEOXYGLYCOSES AND 2-AMINO-2-DEOXYGLYCOSIDES FROM GLYCALS" ABSTRACT OF THE DISCLOSURE, 0-acylated-2-azido-2-deoxy glycosyl nitrates are used to prepare 0-acylated-2-azido-2-deoxy glycosyl halides. The halides are useful in the preparation of 0-acetylated-2-azido-2-deoxy glycosides which in turn, can be reduced to 2-amino-2-deoxy glycosides. Of particular interest are the syntheses of 2-amino-2-deoxy glycosides which correspond to the terminal units of the antigenic determinant for the human A blood group. Attachment of these glycosides to a solid support provides immunoabsorbents which effectively and preferentially absorb anti-A-antibodies from blood plasma.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted October 27, 1981. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended October 27, 1998.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.