6'-n-alkyl and 6',6'-di-n-alkyl derivatives of fortimicins a and b

Abstract From the Canadian patent

Novel fortimicin derivatives having antibiotic activity represented by the formula, wherein R1 is loweralkyl R2 is hydrogen or loweralkyl and, R3 is selected from the group consisting of hydrogen acyl, hydroxyacyl, aminoacyl, N-monoloweralkylaminoacyl N,N-di, loweralkylaminoacyl, hydroxy-substituted aminoacyl or an aminoacid residue, loweralkyl, hydroxyloweralkyl aminolower-, alkyl, N-monoloweralkylaminoloweralkyl N,N-diloweralkyl-, aminoloweralkyl or hydroxy-substituted aminoloweralkyl; and the pharmaceutically acceptable salts thereof inter-, mediates useful in their preparation compositions employing, the compounds and methods of using the compounds.