2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphanes

Abstract From the Canadian patent

2-(2-Alkoxyethyl)-2'-hydroxy-6,7-benzomorphanes of general formula, I, wherein R1 is methyl, ethyl or propyl; R2 is hydrogen methyl or ethyl; and, R is a group of formula , or , (wherein R4 is hydrogen or methyl; R5 is methyl ethyl or propyl; and n in 1, or 2) and pharmaceutically acceptable acid addition salts thereof. The compounds, which may be in the form of racemates or racemic mixtures and optically active compounds, exhibit an analgesic activity and may therefore be useful for the control of pain. A process for the preparation of the compounds and their use in pharmaceutical compositions are described and exemplified.