Process for the preparation of clavulanic acid esters
CA 1097653 A · Owner: Beecham Group Limited · Inventors: Howarth, Thomas T.; Ponsford, Roger J.; Harbridge, John B.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for the preparation of a compound of the formula (1):, (I), or a salt or ester thereof wherein R is a methyl or ethyl group which process comprises the reaction of clavulanic acid or a salt or ester thereof with an oxonium salt of the formula (II): R3O? X.THETA. (II), wherein R is a methyl or ethyl group and X.THETA. is an anion and thereafter if desired performing one or both of the following reactions: (a) converting the thus formed ester into the acid or salt and (b) converting the thus formed acid or salt into an alternative ester or alternative salt. The compounds of formula (I) have utility as additives to enhance the effectiveness of penicillins and cephalosporius. The …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted March 17, 1981. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended March 17, 1998.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.