2,6-bis-(aminoacylamino)-benzo-1,2-d:5,4-d'- bisthiazoles and 2-amino-6-(aminoacylamino)-benzo- 1,2-d:5,4-d'-bisthiazoles, processes for the production and pharmaceuticals

Abstract From the Canadian patent

This invention relates to novel derivatives of 2,6bisamino-benzo1,2-d:5,4-d'-bisthiazole of formula wherein R1 each is hydrogen or alkyl, R2 is hydrogen but at least one of R2 is, (wherein R5 is hydrogen alkyl, alkylaminoalkyl, carboxyalkyl, alkoxyalkyl phenyl, morpholino, or optionally substituted cycloalkyl; R6 is hydrogen, alkyl, alkylaminoalkyl or alkoxyalkyl; or R5 and R6 together with the nitrogen atom form a 5-, 6- or 7- membered heterocyclic ring; and A is alkylene); and R3 and R4 each is hydrogen chlorine, bromine, alkyl, alkoxy, acyl carboxy, alkoxycarbonyl, carbamoyl, phenyl trifluoromethyl, nitro, cyano or, amino and acid addition salts thereof. The novel compounds exhibit …