Assays utilizing localized electromagnetic radiation sources

Abstract From the Canadian patent

Abstract of the Disclosure, Chemical species including biological materials such as enzymes, substrates, antibodies, antigens and the like are, determined in very small quantities (down to picomole ranges) through the use of electromagnetic radiation generating reactions such as those catalyzed by light emitting enzyme systems of the bacterial luciferase and fire-fly luciferase types. The sensitivity of the detection systems is increased by concentrating and localizing at least one component of the electromagnetic radiation generating reaction onto a solid support material. The component may thus be immobilized and solubilized. The localized, immobilized component is generally contacted …