5-nor-bicyclomycin-5-one derivatives

Abstract From the Canadian patent

Derivatives of 5-norbicyclomycin of the formula wherein R represents an unsubstituted or substituted monovalent hydrocarbon radical in which one two or more carbon, atoms can be replaced by heteroatoms and X represents a bi-, valent group of the formula -O- or -N(R')wherein R' has, one of the meanings assigned to R whilst R and R', if both, have a meaning which is different from hydrogen can also be, linked to each other through a C-C bond or an oxygen sulphur, or nitrogen atom, and corresponding compounds in which at least, one hydroxyl group is protected and salts of said compounds, provided they contain salt-forming groups are useful as anti-, biotics, especially against …