2-(4-phenyl-4-hydroxypiperidinomethyl) tetralone and indanone compounds

Abstract From the Canadian patent

Tetralone and indanone compounds of the formula wherein R1 is H, OH, alkoxy of 1-4 carbon atoms cycloalkoxy of, 3-6 carbon atoms, F, Cl Br, alkanoyloxy of 1-6 carbon atoms;, R2 is OH or alkoxy of 1-4 carbon atoms or R1 and R2 collectively are methylenedioxy; R3 is H or CH3; Ar is phenyl or phenyl substituted by up to 5 of alkyl of 1-4 carbon atoms alkoxy of, 1-4 carbon atoms, F, Cl, Br or CF3; n is 1 or 2 and physiological-, ly acceptable acid addition salts thereof are central nervous, system depressants. They may be prepared by certain specified and recited reactions of compounds containing the grouping or, pracursions thereof.