Active derivatives of methylamine, therapeutic compositions containing the same and processes for preparing the said derivatives and compositions

Abstract From the Canadian patent

n-Butylamine derivatives having the general formula: I, and the pharmaceutically acceptable acid addition salts thereof wherein R4 represents hydrogen, propargyl or 2-hydroxyethyl R5 represents methyl, propargyl, 2-hydroxyethyl 3-hydroxy-n-, propyl or R4 and R5, when they are taken together represent, methylene, ethylene, trimethylene ethylidene or -CH2-CH2-O-, CH2-CH2- and R2 is such that : - when R4 repsesents hydrogen and R5 represents methyl R2, represents n-propyl, isopropyl, isobutyl or allyl - when R4 represents hydrogen and R5 represents propargyl 2-hydroxyethyl or 3-hydroxy-n-propyl or when R4 and R5 are identical and each represent propargyl or 2-hydroxyethyl or when R4 and R5 are …