3-((s)-1'-phenylethylamino) propylaminobleomycin, non-toxic salt thereof, and method for producing same

Abstract From the Canadian patent

Novel 3-(S)-1'-phenylethylaminopropylaminobleomycin obtained by reacting a reactive derivative of the carboxyl group of bleomycinic acid with N-(S)-1'phenylethyl-1,3-diaminopropane, a non-toxic salt of said novel bleomycin, and a method for producing the novel bleomycin. Because of much reduction in the side effect causing plumonary fibrosis, the novel bleomycin is more useful than a commercial bleomycin complex which gives rise to said undesirable side effect.