3,11-dihydro-6h-pyrazolo (1.5-a) pyrazolo (4'3':5,6) pyrido-(4,3-d) pyrimidin-6-one and derivatives thereof

Abstract From the Canadian patent

New 3,11-dihydro-6H-pyrazolo1,5-apyrazolo4',3':5,6pyrido4,3-dpyrimidin-6-one and new derivatives thereof use-, ful as antiinflammatory agents, have the general formula wherein R1 and R3 each is hydrogen, lower alkyl phenyl or, phenyl-lower alkylene; R2, R4 and R6 each is hydrogen or lower alkyl; R5 is hydrogen, lower alkyl, phenyl-lower alkylene ben-, zoyl, substituted benzoyl wherein the phenyl substituent is halogen, lower alkyl or lower alkoxy, lower alkanoyl lower, alkoxy-lower alkylene, lower alkylthio-lower alkylene amino-, lower alkylene or , alkylene wherein R7 and R8 each is lower alkyl or join in forming piperidine morpholine, thia-, morpholine or piperazine; and acid addition …