Gel column device and use in blood purification and immunoassay

Abstract From the Canadian patent

Hydrophilic insoluble, porous gel particles having binding proteins entrapped therein, and in which a fluid to be tested may be introduced into the volume of gel particles whereby some of the binding sites are occupied. Exposure of the gel particles to radio active tagged material followed by measurement of the radio activity of the unbound or bound tagged material permits an immunological determination of the fluid. The binding proteins in the gel particles are returned to their original state for reuse by treatment with acidic medium to effect detachment of the bound material followed by washing to effect removal of the unbound material and then, drying.