N-substituted-5,6-dihydroxycyclopentano(h)-1,2,3,4-tetrahydroisoquinolines and ethers and esters thereof

Abstract From the Canadian patent

N-substituted cyclopentanoh-1,2,3,4-tetrahydroisoquinolines of the formula, wherein R and R1 represent hydroxy lower alkoxy, lower, alkanoyloxy or aryl-lower alkanoyloxy groups R3 represents, hydrogen or a lower alkyl group and R4 represents a lower alkyl, arylcarbonyl, aryl-lower alkyl, benzhydryi-lower alkyl, lower alkanoyl, aryl-lower alkanoyl benzhydryl-, lower alkanoyl or benzhydrylcarbonyl group and acid, addition salts and quaternary ammonium salts thereof and, pharmaceutical compositions containing the compounds useful for lowering blood pressure in animals.