Method of preparing anti-inflammatory antirheumatic compounds
CA 1053663 A · Owner: Rotta Research Laboratorium S.P.A. · Inventors: Makovec, Francesco; Rovati, Luigi; Senin, Paolo
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Anti-inflammatory antirheumatic compounds having the formula:, (A), wherein n1 and n2 are 2 or 3 are prepared by reacting, 5-methoxy-2-methyl-3-indolyl acetic acid with an N-hydroxyalkyl- N'-chloroalkyl-piperazine in an organic solvent in the presence of a condensation agent, to obtain the corresponding N'- (2 or 3)-chloroalkyl-N-(2 or 3)-(5-methoxy-2-methyl-3indoleacetoxy)-alkyl-piperazine, amidating the N-atom in the indole group in the resulting compound by means of p-chloro-benzoyl chloride to obtain the corresponding N'-(2 or 3)chloroalkyl-N-(2 or 3)-1-(p-chlorobenzoyl)-5-methoxy-2methyl-3-indoleacetoxy-alkyl-piperazine and reacting the latter compound with …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Granted May 1, 1979. A Canadian patent filed before October 1, 1989 lasted 17 years from grant, so its term ended May 1, 1996.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.