Therapeutic compounds and intermediates therefor

Abstract From the Canadian patent

This invention relates to compounds of the formula I, wherein m is 1 or 2, when m is 1, R occupies either the 4or 5-positions of the starting 2-aminopyrimidine but when, R is halogen it occupies only position-5; whem m is 2 the, two R-substituents occupy the 4- and 5-positions of the starting 2-aminopyrimidine, but only one of the two R-substituents can be halogen and it must occupy the 5-position; R is the same of different and is hydrogen F, Cl, Br, alkyl, of from 1 to 4 carbons benzyl, phenyl, or mono-substituted, phenyl wherein the substituent is F Cl, Br, I, alkyl of, from 1 to 4 carbons alkoxy of from 1 to 4 carbons, or trifluoromethyl; provided that when R is halogen and m is 1, R …